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Research Journal of Medical Sciences
Abbreviation: Res. J. Med. Sci
E-ISSN: 3078-2481 | P-ISSN: 3078-2473
Frequency: Half-Yearly
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ANTICANCER ACTIVITY OF SULFONAMIDES CONTAINING HETEROCYCLE COMPOUND SYNTHESIZED BY GREEN CHEMISTRY VIA SILVER NANOPARTICLES (GREEN NANOPARTICLES)- A COMPREHENSIVE REVIEW

ANTICANCER ACTIVITY OF SULFONAMIDES CONTAINING HETEROCYCLE COMPOUND SYNTHESIZED BY GREEN CHEMISTRY VIA SILVER NANOPARTICLES (GREEN NANOPARTICLES)- A COMPREHENSIVE REVIEW


Author(s):Shiwani Jaiswal, Dr. Kumud Madan
Received: 2023-10-21 Accepted: 2023-11-29 Published: 2023-12-25

Abstract
In green chemistry, formulation of nanoparticles are using different natural sources such as plants, bacteria, micro-organisms, fungi, algae, etc. and synthesis of sulphonamides drugs using different conditions and sources such as under neat conditions, in an aqueous medium, PEG-400, green solvents, etc for the synthesis of sulphonamide and their derivatives. The synergistic effects of silver nanoparticles and sulphonamide derivatives in anti-cancer activity present a promising approach for improving cancer treatment outcomes. Their combined action offers advantages such as enhanced anticancer efficacy, reduced drug resistance, and minimized side effects. The combination of silver nanoparticles and sulfonamide drugs holds significant potential for improving anticancer therapies. Further investigations are required to optimize their dosages, explore suitable drug delivery systems, and evaluate their efficacy against different types of cancers. Additionally, understanding their mechanisms of action, investigating their interaction with tumour microenvironments, and exploring potential synergies with other anticancer agents will be vital for future advancements. However, further research is necessary to fully elucidate their optimal usage, evaluate their safety profiles, and translate these findings into effective clinical applications.

Keywords: Green chemistry, Silver nanoparticles, Sulphonamide, Anti-cancer activity




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