Author(s):Varsha Rathi, Pooja Gharde, Ravi Rajdeo, Pooja Raut

Received: May 1, 2026 | Accepted: May 24, 2026 | Published: June 10, 2026

Abstract

Kimura disease is a rare chronic inflammatory disorder predominantly affecting the head and neck region, often presenting as painless subcutaneous masses with associated lymphadenopathy, eosinophilia and raised serum IgE counts. It shows male preponderance, particularly affecting the Asian males of 18-40 yrs age groups. Due to overlapping imaging features, it can mimic vascular malformations and neoplastic conditions. We report a case of a 20 years old male presenting with a gradually enlarging left cheek swelling, initially suspected to be a slow-flow vascular malformation on Ultrasound and referred to tertiary care centre for Digital Subtraction Angiography (DSA). Subsequently patient underwent MRI and retrospectively repeat USG revealed findings suspicious for infective/inflammatory pathology. Cytological examination suggested features in favour of Kimura’s disease and further warranted need of HPE. Excisional biopsy was performed and post-operative histopathological examination confirmed Kimura disease. This case highlights the importance of considering this in differential diagnoses of vascular-appearing soft tissue lesions and underscores the role of histopathology in definitive diagnosis.

Keywords: Kimura disease, Vascular malformation, Cheek Swelling, Eosinophilia, Lymphadenopathy

DOI: 10.5281/zenodo.20622963

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