IMPORTANCE OF SURFACTANTS IN PHARMACEUTICAL PROPDUCT

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IMPORTANCE OF SURFACTANTS IN PHARMACEUTICAL PROPDUCT

Navneet Gupta, Navneet Kumar Verma, Uma Srivastava
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Abstract

Understanding the creation, structure, and properties of emulsions is critical for developing and stabilising food structures. The rising use of surfactants has highlighted the need of discovering molecules with low toxicity and high surface activity qualities. The primary endpoints listed in the Organisation for Economic Cooperation and Development (OECD) standards for food chemical hazard assessment receive a lot of attention. This critical analysis focuses on crucial factors such as acute toxicity, subacute repeated trials, allergies, reproductive toxicity, long-term research, and mutagenicity tests. This article focuses on the association structures of surfactants and food colloids. The huge number of conceivable combinations leads to very sophisticated internal microstructures that include a variety of assemblies such as dispersions, emulsions, foams, gels, and more. Low-mass surfactants have great mobility at the interface, which effectively reduces interfacial tension. Consequently, they rapidly coat the newly created oil-water contact during emulsification. This category highlights monoglycerides, lecithins, glycolipids, fatty alcohols, and fatty acids. In contrast, high-mass surfactants contain protein and carbohydrate groups. Protein molecules can interpenetrate the lipid phase to variable degrees, with specific binding being predominantly determined by electrostatic interactions. Saturation binding for anionic surfactants is pH-independent and appears to be controlled by cooperative hydrophobic interactions. Polysaccharides and small-molecule surfactants are the two most common types of amphiphilic compounds used for emulsion stabilisation

Keywords

AGP (polyglycosides) biosurfactants food safety glycolipides hydrocolloids monoglycerides proteins stabilizers.

Research Journal of
Medical Sciences

Research Journal of
Medical Sciences

Research Journal of Medical Science

Research Journal of Medical Sciences

Research Journal of Medical Sciences

Research Journal of Medical Science

Research Journal of
Medical Sciences

Research Journal of
Medical Sciences